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Apexbio Technology LLC Posaconazole, 171228-49-2, MFCD00941162, 25 mg
Supplier: Apexbio Technology LLC A171825
MF: C37H42F2N8O4, MW: 700.78, Solubility: 35.039mg/mL in DMSO, Appearance: A solid. Posaconazole, also known as SCH 56592 or Noxafil, is a novel triazole antifungal compound that potently inhibits 14alpha-demethylation in a variety of fungi. Posaconzole, an itraconzole derivative with fluorine replacing chlorine in the phenyl ring and hydroxylation in the side chain, binds to the heme cofactor on the active site of 14alpha-demethylase, which converts lanosterol to 14alpha-dimethy lanosterol, resulting in the disruption of the integrity and function of the fungal cell membrane and inhibition of fungal growth.
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