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Medchemexpress LLC Potassium oxonate | 2207-75-2 | 99.9% | 195.17 | 500 MG
Supplier: Medchemexpress LLC HY17511500MG
Potassium oxonate (Potassium azaorotate) is a uricase inhibitor primarily used in research to inhibit the phosphorylation of 5-FU and for creating hyperuricemia animal models. This selective competitive inhibitor blocks hepatic uricase and is metabolized in the gastrointestinal tract, distributing primarily in small intestine cells where it is converted to cyanuric acid.
- Inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate.
- Utilized in animal modeling to create hyperuricemia models.
- Functions as a selective competitive uricase inhibitor.
- Blocks the action of hepatic uricase.
- After metabolism, primarily distributes within the cells of the small intestine.
- Converted to cyanuric acid in the gastrointestinal tract through two pathways.
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