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Medchemexpress LLC Povorcitinib phosphate | 1637677-33-8 | 98.8% | C23H25F5N7O5P | 1 ML
SDP

Catalog No. 5000356174
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Povorcitinib phosphate is a potent and selective JAK1 inhibitor. It is effective in reducing abscesses and inflammatory nodules and can be utilized for studying cutaneous lupus erythematosus (CLE) and lichen planus (LP). It regulates the expression of TNF-α and TGF-β, thereby exhibiting anti-inflammatory activity. In vivo studies have shown that it alleviates liver inflammation and pathological damage and prolongs survival rate in Down Syndrome (DS) carrying Dp16 mouse models.

  • Potent and selective JAK1 inhibitor
  • Effective in reducing abscesses and inflammatory nodules
  • Regulates the expression of TNF-α and TGF-β
  • Exhibits anti-inflammatory activity
  • Alleviates liver inflammation and pathological damage
  • Prolongs mouse survival rate in Dp16 mouse models

Catalog No. 50-003-56174 Supplier Medchemexpress LLC Supplier No. HY145588A10MM/1ML
May include imposed supplier surcharges.
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Povorcitinib phosphate is a potent and selective JAK1 inhibitor. It is effective in reducing abscesses and inflammatory nodules and can be utilized for studying cutaneous lupus erythematosus (CLE) and lichen planus (LP). It regulates the expression of TNF-α and TGF-β, thereby exhibiting anti-inflammatory activity. In vivo studies have shown that it alleviates liver inflammation and pathological damage and prolongs survival rate in Down Syndrome (DS) carrying Dp16 mouse models.

  • Potent and selective JAK1 inhibitor
  • Effective in reducing abscesses and inflammatory nodules
  • Regulates the expression of TNF-α and TGF-β
  • Exhibits anti-inflammatory activity
  • Alleviates liver inflammation and pathological damage
  • Prolongs mouse survival rate in Dp16 mouse models

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