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Enzo Life Sciences PP1 (1mg). CAS: 172889-26-8

Supplier: Enzo Life Sciences BMLEI2750001
A highly potent and selective inhibitor of Src family tyrosine kinases, IC50=5 nM for p56lck; p59fynT=6 nM; p60src=170 nM. Inhibition of Src family kinases by PP1 has been shown to: prevent a-thrombin-stimulated Akt phosphorylation, delay PAF-mediated STAT3 phosphorylation, block Zn2+-induced Ras activation, block adhesion-dependent tyrosine phosphorylation of p105HEF1 5, and inhibit HLA-DR-induced tyrosine phosphorylation without affecting the activation of ERK1/2. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (25mg/ml), slightly soluble in 100% ethanol.
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