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Enzo Life Sciences PP2 (5mg). CAS: 172889-27-9
Supplier: Enzo Life Sciences BMLEI2970005
A potent and selective inhibitor of the Src family tyrosine kinases. Inhibits Lck (IC50=4 nM), Fyn (IC50=5 nM), and Hck (IC50=5 nM). It displays weaker inhibition of EGFR (IC50=480 nM) and no inhibition of ZAP-70 (IC50 100 µM) and JAK2 (IC5050 µM). PP2 is a useful tool for probing the involvement of Src family tyrosine kinases in cellular signaling. Alternative name: AG1879, 4-Amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo 3 4-d pyrimidine. Purity: ≥98% (TLC). Solubility: Soluble in DMSO (25mg/ml). Long Term Storage: -20°C.
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