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Medchemexpress LLC PPI-2458 | 431077-35-9 | 99.7% | 424.53 | 1 ML
SDP

Catalog No. 5000350394
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PPI-2458 is a potent, orally active, selective, and irreversible inhibitor of methionine aminopeptidase-2 (MetAP-2), primarily used in arthritis and lymphoma research.

  • Potent, orally active, selective, and irreversible MetAP-2 inhibitor.
  • Inhibits HUVEC proliferation with a GI50 of 0.2 nM.
  • Inhibits proliferation and MetAP-2 in SU-DHL-16 cells.
  • Reverses joint swelling and inflammation in PG-PS-induced arthritis models.
  • Suppresses tumor growth in severe combined immunodeficient mice with SR tumor xenografts.

Catalog No. 50-003-50394 Supplier Medchemexpress LLC Supplier No. HY1373110MM/1ML
May include imposed supplier surcharges.
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PPI-2458 is a potent, orally active, selective, and irreversible inhibitor of methionine aminopeptidase-2 (MetAP-2), primarily used in arthritis and lymphoma research.

  • Potent, orally active, selective, and irreversible MetAP-2 inhibitor.
  • Inhibits HUVEC proliferation with a GI50 of 0.2 nM.
  • Inhibits proliferation and MetAP-2 in SU-DHL-16 cells.
  • Reverses joint swelling and inflammation in PG-PS-induced arthritis models.
  • Suppresses tumor growth in severe combined immunodeficient mice with SR tumor xenografts.

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