PR-Set7 Protein, Human is a recombinant, tag-free fragment of the human PR-Set7 (KMT5A/SETD8) methyltransferase supplied as a lyophilized powder for research use. It monomethylates histone H4 at Lys20 and is provided with characterization and activity data suitable for enzymatic assays, antibody validation, and cell biology studies.
- Recombinant human protein fragment that monomethylates histone H4 at Lys20.
- Tag free for applications requiring unmodified protein.
- Lyophilized powder formulation for long-term storage and convenient reconstitution.
- Purity >95.0% as determined by reducing SDS-PAGE.
- Approx. 18 kDa molecular weight and 98 amino acids in the provided fragment.
- Expressed in E. coli and supplied with low endotoxin (<1 EU/μg).
- Storage recommended at -20°C; aliquot and store at -80°C for extended stability.
- Biological activity characterized: ED50 26.51 ng/mL (cell proliferation assay).