Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Cayman Chemical PralsetInIb 10mg
Supplier: Cayman Chemical 3318110 MG
An inhibitor of RET (IC50s = 0.4, 0.3, 0.4, and 0.4 nM for wild-type RET, RETV804L, RETV804M, and RETM918T, respectively); selective for RET over VEGFR2 (IC50 = 35 nM) and a panel of 371 kinases at 300 nM; inhibits a CCDC6-RET fusion protein and autophosphorylation of RET in Ba/F3 cells expressing a KIF5B-RET fusion protein (IC50s = 0.4 and 5 nM, respectively); induces tumor regression in a KIF5B-RET-positive PDX mouse model of NSCLC at 30 mg/kg
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?