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Medchemexpress LLC Pratensein | 2284-31-3 | 1 MG
Supplier: Medchemexpress LLC HYN79811MG
Pratensein, a flavonoid, ameliorates β-amyloid-induced cognitive impairment in rats by reducing oxidative damage and restoring synapse and brain-derived neurotrophic factor (BDNF) levels. It attenuates neuronal degeneration and apoptosis in the hippocampus, and reduces IL-1β, TNF-α overexpression, astrogliosis, and microgliosis induced by Aβ1-42. Pratensein suppresses NF-κB activation and improves spatial learning and memory in Alzheimer's disease rat models.
- Ameliorates β-amyloid-induced cognitive impairment.
- Reduces oxidative damage; restores synapse and BDNF levels.
- Attenuates neuronal degeneration and apoptosis.
- Suppresses NF-κB activation in hippocampus.
- Improves spatial learning and memory in Alzheimer's models.
- Purity: 99.92%.
- Appearance: solid, white to off-white.
- Storage: -20°C, sealed.
- For research use only.
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