Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Prazosin hydrochloride | 19237-84-4 | 99.89% | 500 MG
Supplier: Medchemexpress LLC HYB0193A500MG
Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist, primarily used for research into high blood pressure and alcohol use disorders. It potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC50 of 0.15 nM, and also inhibits organic cation transporters OCT-1 and OCT-3 with IC50s of 1.8 and 13 μM, respectively.
- CNS-active α1-adrenergic receptor antagonist
- Potently inhibits norepinephrine (NE)-stimulated 45Ca efflux
- Inhibits organic cation transporters OCT-1 and OCT-3
- Inhibits proliferation, migration, and invasion of U251 and U87 cells, and promotes apoptosis via the PI3K/AKT/mTOR signaling pathway
- Peripheral administration can suppress central α1-adrenergic-mediated hyperexcitability and stress-induced anxiety
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?