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Vector Biolabs NK2 transcription factor related, locus 5 (Drosophila) Adenovirus (Ad-NKX2.5/CSX)
Supplier: Vector Biolabs 1417
The Nkx family of homeobox containing transcription factors are differentially expressed and regulate the production of tissue specific target genes. Some members of the Nkx family include TTF-1 (also designated Nkx-2.1), Nkx-2.2, Nkx-2.5 (also designated cardiac specific homeobox protein CSX), Nkx-2.6, Nkx-3.1, Nkx-3.2, Nkx-6.1 and Nkx-6.2. TTF-1 is primarily observed in adult thyroid and lung. Nkx-2.2 and Nkx-6.1 are required for pancreatic B-cell differentiation, and Nkx-2.5 and Nkx-2.6 are involved in normal cardiac development. Nkx-3.1 is predominantly expressed in developing and adult prostate tissue.
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