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Vector Biolabs STAT3 interacting protein 1 Adenovirus (Ad-STAT3IP)
Supplier: Vector Biolabs 1432
Genetic and biochemical studies have led to the identification of the Stat3-Interacting Protein STATIP1. The preferential association of STATIP1 with inactive (i.e., unphosphorylated) Stat3 suggests that it may contribute to the regulation of Stat3 activation. Overexpression of the Stat3-binding domain of STATIP1 blocks Stat3 activation, nuclear translocation, and Stat3-dependent induction of a reporter gene.
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