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Cayman Chemical Precelys 15 mL Hard TIsue 1BOX
Supplier: Cayman Chemical 169121 BOX
IsoprostanesareprostaglandinPG-likeproductsof freeradicalinducedlipidperoxidation.{320} Althoughtheisoprostanes derived from arachidonic acid are the best characterized manyother polyunsaturated fatty acids can form isoprostanes.{7323} (±)5-iPF2a-VI is one of dozens of possible stereo- and regioisomeric isoprostanes which can be formed from arachidonic acid. To date the most extensively studied of these is 8-isoprostane (8-epi-PGF2a iPF2a-III).{30645011} However 8-isoprostane is a minor isoprostane constituent when compared to some of the other isomers which form in natural conditions of oxidative stress.{8367} (±)5-iPF2a-VI is an isoprostane from the unique Type VI class of isoprostanes. This class has been shown to be one of the major isoprostane products in contrast to 8-isoprostane. In addition to being produced in greater abundance than 8-isoprostane Type VI isoprostanes form internal lactones which facilitates their extractio an purificationfrombiological samples.8367940869106390
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