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Cayman Chemical Precelys 24 CovR of ContaI 1ea
SDP

Supplier:  Cayman Chemical 387181 EA

Encompass

A TYK2 inhibitor (Ki 4.8 nM) selective for TYK2 over JAK1 -2 and -3 (Kis 83.8 27.6 and 253 nM respectively) selectively inhibits TYK2-mediated IL-12-induced phosphorylation of STAT4 over JAK1-mediated IL-6-induced phosphorylation of STAT3 and JAK2-mediated erythropoietin-induced phosphorylation of STAT5 in cell-based assays (EC50s 380 2000 and 1700 nM respectively)

Catalog No. 50-291-7931


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