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Cayman Chemical Precelys EvolutIon DIgItal 1ea

Supplier: Cayman Chemical 386931 EA

A nucleoside analog a TK1 substrate inhibits TK1 and TK2 (Kis 6 and 10 UM respectively) inhibits HIV-1 reverse transcriptase (EC50 5 nM) and the replication of HIV-1 in MT-4 cells (EC50 5 nM) decreases mtDNA levels and the OCR and induces upregulation of CD11b in OCI-AML-2 and MV4-11 cells reduces tumor growth in an OCI-AML-2 AML mouse xenograft model at 50 mg/kg a radiolabeled form is commonly used as a PET tracer for in vivo imaging of tumors
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