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Cayman Chemical Precelys EvolutIon Ful M 1ea

Supplier: Cayman Chemical 185741 EA

An irreversible EGFR tyrosine kinase inhibitor that blocks ATP-dependent autophosphorylation of EGFR carrying the T790M mutation as well as an L858R mutation (IC50 8 nM) effective in mouse models of lung cancer driven by EGFRT790M
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