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Cayman Chemical Precelys EvolutIon Touch 1ea
SDP

Supplier:  Cayman Chemical 387071 EA

Encompass

An inhibitor of the cardiac late INa (IC50 0.88 UM in HEK293 cells expressing the a subunit of Nav1.5) selective for the cardiac late INa over a panel of 11 cardiac ion channels at 1 UM as well as Nav1.1-1.4 and Nav1.6-1.8 (IC50s ≥5 UM for all) reverses anemone toxin-II-induced activation of MAPD90 in isolated rabbit hearts (EC50 0.72 UM) inhibits S-T segment elevation in a rabbit model of cardiac ischemia-reperfusion injury induced by occlusion of the left anterior descending artery (EC50 0.19 UM) decreases the incidence of ventricular tachycardia-ventricular fibrillation and mortality in a rabbit model of ischemia-induced arrhythmia induced by left circumflex artery ligation

Catalog No. 50-291-6514


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