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Apexbio Technology LLC Prednisone 53-03-2 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B21485.1
Prednisone is a synthetic glucocorticoid which functions primarily as an agonist of the glucocorticoid receptor (GR) Upon binding to the GR prednisone induces receptor translocation into the nucleus initiating the regulation of gene expression involved in inflammation immune responses and cellular proliferation Due to its immunosuppressive mechanism prednisone is widely used as an experimental tool in biomedical studies exploring inflammatory diseases autoimmune conditions and immune signaling pathways Structurally prednisone is a corticosteroid derivative characterized by specific modifications that affect its pharmacodynamics and bioavailability In laboratory settings prednisone assists researchers in dissecting glucocorticoid-mediated physiological and molecular events evaluating receptor-ligand interactions and examining downstream signaling mechanisms in various cell-based assays and animal models
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