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Cayman Chemical Preladenant 10mg
Supplier: Cayman Chemical 2221010 MG
An adenosine A2A receptor antagonist (Kis = 1.1 and 2.5 nM for human and rat receptors, respectively); selective for A2A receptors over A1, A2B, and A3 receptors, with Ki values greater than 1,000 nM, and a panel of receptors enzymes and ion channels; inhibits A2A receptor agonist-induced adenylate cyclase activity (Kbs = 1.3 and 0.7 nM for human and rat receptors, respectively); inhibits catalepsy induced by haloperidol in rats by 77 and 70% after 1 and 4 hours, respectively (1 mg/kg); increases the efficacy of L-DOPA when used in combination with eltoprazine
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