Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000386954

Medchemexpress LLC Prexasertib (dihydrochloride) | 1234015-54-3 | 99.4% | 438.31 | 1 ML
SDP

Catalog No. 5000386954
Encompass_Preferred

Prexasertib dihydrochloride is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. It causes double-stranded DNA breakage and replication catastrophe, leading to apoptosis, and exhibits potent anti-tumor activity. It also inhibits CHK2 and RSK1.

  • Selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor.
  • Causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis.
  • Shows potent anti-tumor activity.
  • Inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM).

Catalog No. 50-003-86954 Supplier Medchemexpress LLC Supplier No. HY18174A10MM/1ML
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

Prexasertib dihydrochloride is a selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor with a Ki of 0.9 nM and an IC50 of <1 nM. It causes double-stranded DNA breakage and replication catastrophe, leading to apoptosis, and exhibits potent anti-tumor activity. It also inhibits CHK2 and RSK1.

  • Selective, ATP-competitive second-generation checkpoint kinase 1 (CHK1) inhibitor.
  • Causes double-stranded DNA breakage and replication catastrophe resulting in apoptosis.
  • Shows potent anti-tumor activity.
  • Inhibits CHK2 (IC50=8 nM) and RSK1 (IC50=9 nM).

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.