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Medchemexpress LLC Prexasertib dihydrochloride | 1234015-54-3 | MFCD25977016 | 99.7% | 10 MG
SDP

Supplier:  Medchemexpress LLC HY18174A10MG

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Prexasertib dihydrochloride is a selective, ATP-competitive CHK1 inhibitor used in preclinical research to probe checkpoint signaling, replication stress, and DNA damage-induced apoptosis. It is suitable for biochemical and cellular assays investigating antitumor mechanisms and pathway dependencies.

  • High potency against CHK1 (Ki 0.9 nM; IC50 <1 nM).
  • Also inhibits CHK2 and RSK1 at low nanomolar concentrations (CHK2 IC50 8 nM; RSK1 IC50 9 nM).
  • Available as solid powder and as DMSO solutions for flexible assay formats.
  • Reported high purity appropriate for preclinical studies.
  • Useful for studies of DNA damage response, replication catastrophe, and apoptosis.

Catalog No. 50-002-95035


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