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Cayman Chemical PRfluorobutylsulfonamID 100mg

Supplier: Cayman Chemical 37365100 MG

A TDO inhibitor (IC50 2 UM) selective for TDO over IDO MAO-A and MAO-B as well as a panel of various receptors and transporters at 10 UM reverses tumoral immune resistance in a TDO-overexpressing P815B mastocytoma syngeneic model using mice immunized with the P815 antigen P1A prevents decreases in the number of dopaminergic neurons and increases in microglial cell volume in the substantia nigra and inhibits decreases in intestinal transit in a mouse model of rotenone-induced Parkinsons disease at 50 mg/kg
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