Biotium Primary Antibody c Myb MYB286 CF740 1/EA

Supplier:  Biotium BNC740286100

The highly leukemogenic avian retrovirus E26 contains two oncogenes v-Myb and v-Ets which are expressed together as a fusion protein The cellular homolog of v-Myb designated c-Myb encodes a transcription factor Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel leads to activation of its ability to transform hemopoietic cells c-Myb is expressed preferentially but not exclusively in immature hemopoietic cells and its expression decreases as cells differentiate Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors

Catalog No. 50-004-99531