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Biotium Primary Antibody CD20 109-3C2 CF740 1/EA
Supplier: Biotium BNC740355500
Recognizes a protein of 30-33 kDa which is identified as CD20 (Workshop V Code CD20 12 Workshop IV Code B17) It recognizes an extracellular domain of CD20 It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells being absent from all other leukocytes and tissues CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation It acts as calcium channel involved in B cell activation and cell cycle progression Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of
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