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Biotium Primary Antibody CD227 EMA Episialin Mucin 1 GP1.4 CF740 1/EA
Supplier: Biotium BNC740159500
In Western blotting this antibody recognizes proteins in MW range of 265-400 kDa identified as different glycoforms of EMA This MAb reacts with the DTRP epitope in the tandem repeats Thealpha subunit has cell adhesive properties It can act both as an adhesion and an anti-adhesion protein EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack The beta subunit contains a C-terminal domain which is involved in cell signaling through phosphorylations and protein-protein interactions In immunohistochemical assays it superbly stains routine formalin/paraffin carcinoma tissues Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
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