Biotium Primary Antibody CD28 C28/74 CF740 1/EA

Supplier:  Biotium BNC740074500

Recognizes a glycoprotein of 44-88 kDa which is identified as CD28 It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells Besides its co-stimulation role CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death CD28 is also expressed on human fetal NK cells and some NK cell lines whereas on murine NK cells the CD28 expression is much broader Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors

Catalog No. 50-005-00525