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Biotium Primary Antibody CD43 84-3C1 CF740 1/EA
Supplier: Biotium BNC740342100
This antibody recognizes a cell surface glycoprotein of 95/115/135 kDa (depending upon the extent of glycosylation) identified as CD43 (Workshop III) 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43 No reactivity has been observed with reactive B-cells So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma especially a low-grade lymphoma rather than a reactive B-cell population When CD43 antibody is used in combination with anti-CD20 effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma x000D x000D Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low
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