Biotium Primary Antibody CD86 BU63 CF740 1/EA

Supplier:  Biotium BNC740193500

Recognizes a protein of 70 kDa which is identified as CD86 CD86 along with CD80/B71 is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4 a cancer immunotherapy target It is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation Since CD86 has rapid kinetics of induction it is believed to be the major CD28 ligand expressed early in the immune response It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkins disease x000D x000D Primary antibodies are available purified or with a selection of fluorescent CF Dyes and other labels CF Dyes offer exceptional brightness and photostability Note Conjugates of

Catalog No. 50-004-99456