Biotium Primary Antibody Testosterone 4E1G2 CF740 1/EA

Supplier:  Biotium BNC740250500

This MAb is highly specific to testosterone Its affinity constant for testosterone is approximately 1010 M-1 In competitive binding immunoassay it reacts with testosterone 100% 11-beta-hydroxy testosterone 3 3% 17-alpha-methyl testosterone and lt 0 1% 5-alpha DHT 0 8% estradiol and lt 0 1% and progesterone and lt 0 1% Testosterone a steroid hormone from the androgen group is derived from cholesterol Testosterone is primarily secreted in the testes but the ovaries and adrenal glands also produce smaller amounts It is the principal male sex hormone and is responsible for the maturation of sex organs and the development of male secondary sex characteristics The hormone is also involved in the growth of muscle mass and increases bone density and maturation It functions by activating the androgen receptor and converting to estradiol and activation of estrogen receptors Testosterone has been employed therapeutically to treat many conditions including infertility lack of libido osteoporosis

Catalog No. 50-005-00859