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Cayman Chemical PrImary Vascular EIcosnoId M

Supplier: Cayman Chemical 196671 EA

An inhibitor of mutant IDH1 (IC50s 9 15 and 17 nM for IDH1 mutants R132C R132H and R132G respectively) causes a dose-dependent reduction in 2-hydroxyglutarate and overcomes the block of differentiation in AML cells expressing mutant IDH1
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