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Medchemexpress LLC Pristimerin | 1258-84-0 | 464.64 | 5 MG
Supplier: Medchemexpress LLC HYN19375MG
Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM. It is also known as Celastrol methyl ester. This compound is used for research purposes.
- Potent and reversible monoacylglycerol lipase (MGL) inhibitor.
- Inhibits angiogenesis by suppressing VEGFR2 signaling pathways.
- Exhibits anti-inflammatory properties.
- Demonstrates anti-tumorigenic properties and cytotoxicity against various human cancer cell lines.
- Attenuates activation of the VEGF-induced VEGFR2-mediated signaling pathway.
- Reduces vessel density in synovial membrane tissues.
- Decreases expression of pro-angiogenic factors like TNF-α, Ang-1, and MMP-9 in sera.
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