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Medchemexpress LLC Pritelivir mesylate hydrate | 1428321-10-1 | C19H24N4O7S3 | 5 MG
Supplier: Medchemexpress LLC HY15303B5MG
Pritelivir mesylate hydrate, also known as BAY 57-1293 mesylate hydrate, functions as an inhibitor of the viral helicase-primase complex. It demonstrates antiviral activity both in vitro and in animal models against herpes simplex virus (HSV) infection.
- Effective against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with an IC50 of 0.02 μM.
- First in class of antiviral agents targeting the viral helicase-primase enzyme complex.
- Significantly increases survival in animal models at doses of 0.03-45 mg/kg.
- Reduces mortality against HSV-1, E-377 at doses of 0.3-30 mg/kg.
- Protective against HSV-2, strain MS, in combination with Acyclovir.
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