Invitrogen™ Human PRKCN (PKD3), GST Tag Recombinant Protein

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Specifications

• Accession Number: O94806
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
• Gene ID (Entrez): 23683
• Molecular Weight (g/mol): 127.9 kDa
• Name: Human PRKCN (PKD3), GST Tag
• Quantity: 10 μg
• Regulatory Status: For research use only. Not for use in diagnostic procedures
• Gene Alias: 4930557O20Rik; 5730497N19Rik; EPK2; nPKC-D1; nPKC-mu; nPKC-nu; PKCM; PKC-MU; Pkcnu; PKC-NU; PKD; PKD1; PKD3; PRKCM; Prkcn; PRKD1; Prkd3; Protein kinase C mu type; protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; protein kinase D; protein kinase D1; protein kinase D3; protein kinase EPK2; Serine/threonine-protein kinase D1; serine/threonine-protein kinase D3
• Common Name: PRKD3
• KinaseFamily: PKN
• Product Type: PRKCN (PKD3) Recombinant Human Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: GST-tag
• Sequence: Full length
• Content And Storage: -80°C, Avoid Freeze/Thaw Cycles
• Expression System: Insect cells
• Protein Family: Kinase and inhibitors
• Form: Liquid
• Protein Subtype: Serine/threonine kinase
• Purity or Quality Grade: 95% by SDS-PAGE