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Medchemexpress LLC Procaine hydrochloride | 51-05-8 | 97.9% | 25 G
SDP

Supplier:  Medchemexpress LLC 25GHYB0546A

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Procaine hydrochloride is a DNA-demethylating agent with multiple targets, characterized by a slow onset and short duration of action. It exhibits growth-inhibitory effects in human cancer cells by inducing mitotic arrest. Additionally, it functions as an excitant of limbic system cells and modifies synaptic transmission in certain amygdala output pathways. It can competitively inhibit the 5-HT3 receptor-mediated inward current in whole-cell patch clamp recordings with a KD of 1.7 microM.

  • Inhibits 5-HT3 receptor-mediated inward current (KD of 1.7 microM).
  • Reduces 5-methylcytosine DNA content by 40% and demethylates hypermethylated CpG islands.
  • Exhibits growth-inhibitory effects in cancer cells by causing mitotic arrest.
  • Excites limbic system cells and alters synaptic transmission in amygdala output pathways.

Catalog No. 50-004-06584


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