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Medchemexpress LLC Procion blue HB | 12236-82-7 | 97.93% | 5 MG
SDP

Catalog No. 5000409743
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Procion Blue HB (Reactive Blue 2) is a purinergic antagonist intended for research use only. It acts as an ATP receptor antagonist and induces Ca2+ oscillations in HeLa cells.

  • Enhances a Ca2+ response to histamine linked to the PLC cascade.
  • May activate the PLC cascade in an extracellular Ca2+-dependent manner, inducing Ca2+ oscillations.
  • Increases K+ secretion in a dose-dependent manner in rat cochlea strial marginal cells.
  • Exhibits antagonistic activities at P2Y4, with potency correlating to K+ secretion.
  • Potent inhibitor of a protein kinase isolated from thylakoids, with noncompetitive inhibition (Ki of 8 μM for membrane-bound kinase, 6 μM for purified kinase).
  • Selectively inhibits responses mediated via the P2y-purinoceptor within a limited concentration range.
  • Blocks ATP-induced oscillation at concentrations of 0.3-10 μM in a concentration-dependent manner.

Catalog No. 50-004-09743 Supplier Medchemexpress LLC Supplier No. HYD09655MG
May include imposed supplier surcharges.
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Procion Blue HB (Reactive Blue 2) is a purinergic antagonist intended for research use only. It acts as an ATP receptor antagonist and induces Ca2+ oscillations in HeLa cells.

  • Enhances a Ca2+ response to histamine linked to the PLC cascade.
  • May activate the PLC cascade in an extracellular Ca2+-dependent manner, inducing Ca2+ oscillations.
  • Increases K+ secretion in a dose-dependent manner in rat cochlea strial marginal cells.
  • Exhibits antagonistic activities at P2Y4, with potency correlating to K+ secretion.
  • Potent inhibitor of a protein kinase isolated from thylakoids, with noncompetitive inhibition (Ki of 8 μM for membrane-bound kinase, 6 μM for purified kinase).
  • Selectively inhibits responses mediated via the P2y-purinoceptor within a limited concentration range.
  • Blocks ATP-induced oscillation at concentrations of 0.3-10 μM in a concentration-dependent manner.

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