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AdipoGen Progranulin h ELISA KitmAb
Supplier: AdipoGen AG45B0027KI01
Colorimetric Sandwich ELISA Assay. Detects human progranulin in cell culture supernatants, serum and plasma and allows the detection of Progranulin FTLD mutations. Range 0.063 to 4ng/ml. Sensitivity 60pg/ml. Samples Cell Culture Supernatant, Plasma, Serum. Progranulin PGRN is a widely expressed pluripotent growth factor that plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. In addition, PGRN has also been linked to tumorigenesis. New cutting-edge publications have shown that progranulin might be a biomarker not only for FTLD but also for other types of Alzheimer‘s disease AD. This new data even suppose the potential of progranulin to be a biomarker for MCI Mild Cognitive Impairment, which would be a hallmark in AD research. Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory diseases like arthritis.
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