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Medchemexpress LLC Proguanil (hydrochloride) | 637-32-1 | 99.2% | 25 MG
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Supplier:  Medchemexpress LLC 25MGHYB0806A

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Proguanil hydrochloride is an antimalarial proagent that is metabolized to its active form, Cycloguanil. It acts as a dihydrofolate reductase (DHFR) inhibitor. It is intended for research use only and not for patient use. The combination of Atovaquone and Proguanil shows in vitro synergy and activity against gametocytes and pre-erythrocytic (hepatic) stages of malaria parasites.

  • Metabolized to active form, cycloguanil
  • Dihydrofolate reductase (DHFR) inhibitor
  • Shows in vitro synergy with atovaquone
  • Active against gametocytes and pre-erythrocytic stages of malaria parasites
  • Enhances atovaquone effect
  • Reversibly inhibits 5-HT3 receptor responses

Catalog No. 50-004-50808


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