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Medchemexpress LLC Promethazine hydrochloride | 58-33-3 | MFCD00012652 | 99% | 320.88 | 500 MG
SDP

Catalog No. 5000365907
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Promethazine hydrochloride is an orally active phenothiazine derivative with antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. It is a potent H1 receptor antagonist and a mAChR antagonist, also showing affinity for 5-HT2A and 5-HT2C receptors.

  • Inhibits adipocyte formation in a dose-dependent manner
  • Decreases expression of peroxisome proliferator activated receptor γ (PPARG)
  • Reduces phosphorylation level of CREB in PDGFRα+ cells
  • Possesses inhibitory effect on ectopic fat cell formation in skeletal muscle in a mouse achilles tendon rupture model
  • Potent H1 receptor antagonist
  • mAChR antagonist
  • Shows affinity for 5-HT2A and 5-HT2C receptors

Catalog No. 50-003-65907 Supplier Medchemexpress LLC Supplier No. 500MGHYB0781
May include imposed supplier surcharges.
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Promethazine hydrochloride is an orally active phenothiazine derivative with antihistaminic (H1), sedative, antiemetic, anticholinergic, and antimotion sickness properties. It is a potent H1 receptor antagonist and a mAChR antagonist, also showing affinity for 5-HT2A and 5-HT2C receptors.

  • Inhibits adipocyte formation in a dose-dependent manner
  • Decreases expression of peroxisome proliferator activated receptor γ (PPARG)
  • Reduces phosphorylation level of CREB in PDGFRα+ cells
  • Possesses inhibitory effect on ectopic fat cell formation in skeletal muscle in a mouse achilles tendon rupture model
  • Potent H1 receptor antagonist
  • mAChR antagonist
  • Shows affinity for 5-HT2A and 5-HT2C receptors

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