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Medchemexpress LLC Propanoic acid, 2-hydroxy-, sodium salt (1:1) | 72-17-3 | 98.0% | 2 ML
Supplier: Medchemexpress LLC HYB2227B2ML
Lactic acid sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator. It induces lysine residues lactylation, functions as an oncometabolite, and has an immune protective role in anti-tumor immunity. It also exhibits antimicrobial activity and can be used as a food preservative.
- Significantly decreases cell proliferation and migration at 20 mM concentration
- Switches cell metabolism towards oxidative phosphorylation
- Increases protein and mRNA expression levels of MCT1 and HCAR1
- Demonstrates CD8+ T cell-dependent tumor growth inhibition in MC38 colon cancer model
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