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Medchemexpress LLC Propargyl-PEG1-Boc | 488150-84-1 | 97.0% | 184.23 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140026
Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. PROTACs are composed of two different ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets a specific protein, utilizing the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl/ether-based PROTAC linker
- Used in PROTAC synthesis
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Utilizes the ubiquitin-proteasome system for targeted protein degradation
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