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Medchemexpress LLC Propargyl-PEG1-SS-PEG1-t-butyl ester | 1807518-78-0 | MFCD28505559 | >98.0% | 320.47 g/mol | C14H24O4S2 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY13069010MG

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Propargyl-PEG1-SS-PEG1-t-butyl ester is a cleavable PEG-based linker containing terminal propargyl (alkyne) groups and a disulfide bond. It is used in bioconjugation workflows such as antibody-drug conjugate and PROTAC synthesis, and as a click-chemistry handle for azide-alkyne cycloaddition.

  • Cleavable disulfide linkage allows intracellular reduction and payload release.
  • Terminal propargyl groups enable copper-catalyzed and strain-promoted click reactions.
  • High purity (>98.0%) suitable for synthetic chemistry applications.
  • Molecular weight 320.47 g/mol and formula C14H24O4S2.
  • Available in small research quantities (5 mg, 10 mg, 25 mg) for lab-scale synthesis.

Catalog No. 50-002-03480


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