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Medchemexpress LLC Propargyl-PEG2-amine | 944561-44-8 | MFCD19160595 | >98.0% | 143.18 g/mol | C7H13NO2 | 10 G
Supplier: Medchemexpress LLC HYW05163410G
Propargyl-PEG2-amine is an alkyne-functionalized PEG2 amine reagent used as a short, hydrophilic linker in bioconjugation chemistry. It features a terminal propargyl (alkyne) group and a primary amine, enabling copper-catalyzed azide-alkyne cycloaddition (CuAAC) and common amide-coupling chemistries for antibody-drug conjugates, PROTACs, and general PEGylation.
- Contains terminal alkyne for click chemistry (CuAAC).
- PEG2 spacer provides a short, hydrophilic linkage.
- Primary amine enables conjugation to activated esters or carboxylic acids.
- Low molecular weight (143.18 g/mol) and liquid form facilitate handling.
- Applicable to ADC linker synthesis, PROTAC assembly, and general bioconjugation workflows.
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