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Medchemexpress LLC Propargyl-PEG3-CH2COOH | 1694731-93-5 | 98.0% | 25 MG
Supplier: Medchemexpress LLC 25MGHY130563
Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules possessing Azide groups. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein, exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Click chemistry reagent with an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc)
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system to selectively degrade target proteins
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