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Medchemexpress LLC Propargyl-PEG3-OCH2-Boc | 888010-02-4 | 302.36 | 250 MG
Supplier: Medchemexpress LLC 250MGHY140031
Propargyl-PEG3-OCH2-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent containing an Alkyne group, capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent containing an alkyne group
- Capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups
- Utilizes two different ligands connected by a linker; one ligand for an E3 ubiquitin ligase and another for the target protein
- Employs the intracellular ubiquitin-proteasome system to selectively degrade target proteins
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