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Medchemexpress LLC Propargyl-PEG4-acid | 1415800-32-6 | 97.0% | 10 G
SDP

Catalog No. 5000339810
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Propargyl-PEG4-acid is a PEG-based PROTAC linker. It can be used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and analogue PROTAC 3, which causes BTK degradation. Propargyl-PEG4-acid is also a click chemistry reagent, featuring an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • PEG-based PROTAC linker
  • Used in synthesis of BTK-IAP PROTACs
  • PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells
  • Click chemistry reagent with Alkyne group
  • Can undergo CuAAc with Azide groups

Catalog No. 50-003-39810 Supplier Medchemexpress LLC Supplier No. HY13048110G
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Propargyl-PEG4-acid is a PEG-based PROTAC linker. It can be used in the synthesis of BTK-IAP PROTACs, including Ibrutinib-based PROTAC 2 and analogue PROTAC 3, which causes BTK degradation. Propargyl-PEG4-acid is also a click chemistry reagent, featuring an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

  • PEG-based PROTAC linker
  • Used in synthesis of BTK-IAP PROTACs
  • PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells
  • Click chemistry reagent with Alkyne group
  • Can undergo CuAAc with Azide groups

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