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Medchemexpress LLC Propargyl-PEG4-acid | 1415800-32-6 | 97.0% | 500 MG
SDP

Supplier:  Medchemexpress LLC HY130481500MG

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Propargyl-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of BTK-IAP PROTACs Ibrutinib-based PROTAC 2 and an analogue PROTAC 3. PROTAC 3 causes BTK degradation with a DC50 of 200 nM in THP-1 cells.

  • PEG-based PROTAC linker
  • Can be used in the synthesis of BTK-IAP PROTACs
  • Click chemistry reagent
  • Contains an alkyne group
  • Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups

Catalog No. 50-003-40833


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