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Medchemexpress LLC Propargyl-PEG5-acid | 1245823-51-1 | 98.0% | 304.34 g/mol | C14H24O7 | 1 G
Supplier: Medchemexpress LLC HY101157250MG
Propargyl-PEG5-acid is a polyethylene glycol-based linker with a terminal propargyl (alkyne) group and a terminal carboxylic acid. It is used as a non-cleavable PEG spacer in bioconjugation, including antibody-drug conjugate and PROTAC synthesis, and as a reagent for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition.
- Terminal carboxylic acid allows amide bond formation with primary amines.
- Five-unit PEG spacer improves solubility and reduces steric hindrance.
- High purity (98.0%) suitable for bioconjugation.
- Applicable to ADC, PROTAC, and general linker development workflows.
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