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Medchemexpress LLC Propargyl-PEG5-Br | 1287660-83-6 | 339.22 | 100 MG
Supplier: Medchemexpress LLC HY138736100MG
Propargyl-PEG5-Br is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an alkyne group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an alkyne group
- Enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide groups
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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