Apexbio Technology LLC Propidium iodide(Synonyms: PI, Propidium iodide solution, PI staining reagent, Propidium iodide nuclear stain), 10mg, CAS: 25535-16-4.

Supplier:  Apexbio Technology LLC B775810

Propidium iodide (CAS 25535-16-4) commonly abbreviated as PI is a fluorescent nucleic acid intercalating dye widely employed in biomedical research Structurally analogous to ethidium bromide PI intercalates into double-stranded DNA molecules without sequence specificity binding approximately one dye per 4 5 base pairs Due to membrane impermeability PI selectively enters cells only when plasma membrane integrity is compromised as occurs during cell death or late apoptosis Upon DNA binding its fluorescence notably increases facilitating detection via fluorescence microscopy spectrometry or flow cytometry PI is routinely utilized for distinguishing necrotic or late apoptotic cells in viability assays apoptosis studies (often paired with Annexin V) and cell cycle analyses

Catalog No. 50-000-61269