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Medchemexpress LLC PROTAC Axl Degrader 2 | 3033401-45-2 | 98.01% | C38H39N11O4 | 1 MG
SDP

Supplier:  Medchemexpress LLC HY1446271MG

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PROTAC Axl Degrader 2 is a potent and selective PROTAC Axl degrader with an IC50 of 1.61 μM. It exhibits anti-proliferation activity and anti-migration activity in vitro. This compound also induces methuosis.

  • Potent and selective PROTAC Axl degrader.
  • Shows anti-proliferation activity in vitro.
  • Demonstrates anti-migration activity in vitro.
  • Induces methuosis.
  • Decreases the abundance of AXL in MDA-MB-231 cells.
  • Significantly inhibits migration in MDA-MB-231 and 4T1 cells.
  • Does not induce systemic toxicity at 25 mg/kg (i.p.) in female balb/c nude mice.

Catalog No. 50-003-56287


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